Alien

Short Answer: Who is Yutani?

There are two sets of bad guys in the Alien series. One set is hive of predatory creatures just doing what they do: consuming, and killing anything in the way of more consumption.

The other set is the Xenomorphs.

Yes, the real enemy is not so much a species minding its own business when humans disturbed it, as much as the humans who did the disturbing and, when they saw the destructive capacity of the Xenos, tried to weaponize-- and monetize-- it.

The corporation with employs, then endangers, the rest of the humans (and androids) is Weyland-Yutani. Over the course of several films, we meet members and learn the stories of members of the Weyland family, including the corporation's founding Weyland.

But... who is Yutani? Aside from a passing glance in one of the versus-Predator crossovers, we don't meet or know anyone from this family who is part of the business, or story. Just one pistol handed to one person.

So, follow that up. What happens next? How does the merger with Weyland happen? And why?

Also, one physical place the story has not gone yet is an Earth colony on the Moon or Mars. We have seen Xenos in many situations, but not in low gravity like the Moon's. Or make it Mars and maybe the Xenos adapt to breathe its CO2 atmosphere, and also, with lower gravity, almost fly.  

Yeah, flying Xenomorphs. That'd be a problem.